Here to help you be ready at every step ahead

Announcer:

YEZTUGO is a prescription medicine used as HIV-1 PrEP (pre-exposure prophylaxis) to reduce the risk of getting HIV-1 in adults and adolescents who weigh at least 77 pounds. You must be HIV negative before and while receiving YEZTUGO.

Important Safety Information

What is the most important information I should know about YEZTUGO?

Before and while receiving YEZTUGO:

You must be HIV negative before you start and while receiving YEZTUGO. Get an HIV test before starting, before each injection, and when your healthcare provider tells you. If you think you were exposed to HIV while receiving YEZTUGO, talk to your healthcare provider as you may need an HIV test.

Please see additional Important Safety Information about YEZTUGO at the end of the video and see Important Facts, including important warnings, at Yeztugo.com.

Talk to your healthcare provider to see if YEZTUGO is right for you.

TEXT ON-SCREEN: On YEZTUGO since 2025

Ian:
I’m lan, and l've been on YEZTUGO since 2025. Professionally, I’m a nonprofit leader and an author, but storytelling is the thread that really connects everything that I do.

TEXT ON-SCREEN: Why I considered YEZTUGO

Ian:
I realized that for me, HIV prevention needed to be something that could work with the way I actually lived my life. You know, I'm constantly on the go between traveling for work, keeping up with my hobbies, and everything else I have going on. A daily pill started to feel like one more thing I had to remember. So when I learned about YEZTUGO, I was interested in how different the dosing schedule was. After the starting dose, YEZTUGO was given twice a year. That stood out to me because instead of trying to make my life fit around a daily pill, I had an HIV prevention option that felt like it could fit into my life.

TEXT ON-SCREEN: My injection experience

Ian:
I definitely had questions before getting my first YEZTUGO injections. One of the biggest things on my mind was what the injection sites would look like afterwards. I was concerned about having bumps that other people might be able to see. I brought that concern directly to my doctor. We talked about the potential side effects, including the fact that injection site bumps can vary in size. Knowing that ahead of time gave me a better idea of what to expect. My experience ended up being different from what I had imagined. Everyone's experience can be different, but my bumps were less noticeable than I expected. I would say I could feel a bump about an inch in size at each injection site.

TEXT ON-SCREEN: Impact YEZTUGO had on me

Ian:
As a Black gay man, I had spent so many years believing that one day HIV would become part of my life and part of my story. What's different for me now is that I don’t look at my future through that same lens. Today, I have YEZTUGO as an HIV prevention option that fits my needs and the way I live my life. 

Announcer:

Important Safety Information (continued)

What is the most important information I should know about YEZTUGO? (continued)

• Some HIV tests may not detect HIV in a person who recently acquired HIV. Tell your healthcare provider if you had a flu-like illness within the last month before starting or while receiving YEZTUGO. Symptoms of new HIV infection include tiredness, fever, joint or muscle aches, headache, sore throat, vomiting or diarrhea, rash, night sweats, and/or enlarged lymph nodes in the neck or groin.
• YEZTUGO does not prevent other sexually transmitted infections (STIs). Get tested for other STIs and practice safer sex by using condoms to reduce the risk of getting STIs.
• YEZTUGO is not approved to treat HIV. You must immediately take other medicines if you get HIV. If you have HIV and only receive YEZTUGO, your HIV may become harder to treat. 
• Follow the YEZTUGO dosing schedule, which includes returning to a healthcare provider for your scheduled injections every 6 months. Missing scheduled injections or tablets can increase your chances of getting HIV.
• To further help reduce your risk of getting HIV:
• Know your HIV status and the HIV status of your partner(s). If they are living with HIV, your risk of getting HIV is lower if they are taking effective HIV treatment.
• Talk to your healthcare provider about all the ways to help reduce the risk of getting HIV.

Who should not receive or take YEZTUGO?

• Do not receive YEZTUGO if you already have HIV or do not know your HIV status.
  If you have HIV, you will need to take other medicines to treat it. YEZTUGO is not approved to treat HIV and is only for reducing the risk of getting HIV before you get it.

What are the possible side effects of YEZTUGO?

• The most common side effects of YEZTUGO are injection site reactions, headache, and nausea. These are not the only possible side effects.
• Reactions at the injection site may include a lump or bump, pain, skin hardening, swelling, itching, redness, bruising, or warmth.
• Rarely, if YEZTUGO is injected incorrectly, serious injection site reactions, like severe damage of the skin or open sores, can occur.
• Tell your healthcare provider if you have any injection site reactions or other side effects that bother you or don’t go away. 

What should I tell my healthcare provider before receiving YEZTUGO? 

• All your medical conditions.
• If you are pregnant or plan to become pregnant. Tell your healthcare provider if you become pregnant while or after receiving YEZTUGO.
• If you are breastfeeding or plan to breastfeed. Talk to your healthcare provider about the best way to feed your baby while you are receiving YEZTUGO.
• All the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. YEZTUGO can remain in your body for up to 9 months after your last injection and can affect other medicines. Keep a list of all your medicines and show it to your healthcare provider and pharmacist. Do not start a new medicine without telling your healthcare provider.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Please see Important Facts about YEZTUGO, including important warnings, at Yeztugo.com.

Important Safety Information voiceover is AI-generated.